Non-Opioid Pain Medicines
Acetaminophen
(generic; Tylenol ®) tablets or capsules
Acetaminophen (Tylenol ®) is a common over-the-counter pain medicine that comes in tablets, capsules, or chewable tablets.
Which one should I buy?
Acetaminophen (Tylenol ®) is usually sold as tablets or capsules. If you have trouble swallowing, you can ask for it in a liquid or chewable form.
The most common tablet/capsule strengths are:
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325mg - Regular strength
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500mg - Extra strength
How much can I take?
Always check with your doctor, but the usual package instructions are:
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Regular strength tablets (325 mg): Take 2 tablets (650 mg) every 4 to 6 hours as needed for pain
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Extra strength tablets (500mg): 1000 mg (2 tablets) every 6 hours as need for pain
Never take more than 3000mg in a 24-hour period. That means no more than 9 regular strength tablets, or 6 extra strength tablets.
How do I take it?
Take acetaminophen with a glass of water or other liquid. You can take it with or without food.
Here are some ways you can use acetaminophen together with your opioids to help your pain:
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If your pain is mild, you can try taking acetaminophen instead of your short-acting (breakthrough) opioid. If your pain doesn’t improve, then try the opioid.
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If you don’t get enough relief from your short-acting (breakthrough) opioid, try taking acetaminophen.
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If you find that the acetaminophen is not helpful, stop taking it. It’s better to focus on things that work for your pain.
How does it work?
Scientists are not sure how it works to help pain. It may improve pain by reducing inflammation.
What are the side effects?
This medication does not usually cause side effects. Rarely, a person may develop an allergic reaction with swelling of the mouth or throat, shortness of breath, or rash. If this happens, call 911.
