
Addiction Worries:
Understanding Opioid Addiction and Dependence
With so much in the news about the opioid epidemic, many people worry about taking opioids to manage their cancer pain. “Addiction” is often top on peoples’ list of concerns, but there can be a lot of confusion about this word and what it means.
Opioid addiction is very different from becoming tolerant to opioids or physically dependent on them. Opioid use disorder (the technical name for opioid addiction) is a serious medical condition that is RARE among people who need opioids to manage cancer pain.
In contrast, tolerance and dependence are common and are part of the body’s normal reaction to using opioids regularly over many weeks to months. Tap on the words below to see their definitions:
Dependence, tolerance, and the bathtub analogy
Think of dependence and tolerance as signs that your body has become “used to” opioids – similar to how you might become used to the temperature of a hot bath. At first the bath feels very hot, but after several minutes you will be comfortable and might even need more hot water feel warm. When you finally get out of the tub, you will probably feel very cold – even if the room felt pleasant before.
Getting used to the hot bath water is like becoming tolerant to opioids. At first you may notice big effects from one dose of your breakthrough opioid. Over a long time, you may not notice as much pain relief from that dose. Side effects like sleepiness may also become less over time.


Feeling cold when you get out of the tub is similar to the withdrawal symptoms that can happen when a person is physically dependent on opioids. Just like shivering when you get out of the tub, a person who suddenly stops taking opioids may have achiness, cramps, nausea, and diarrhea.
Just like your body’s reaction to a hot bathtub, tolerance and dependence are normal PHYSICAL reactions to opioids. They DO NOT mean that you are addicted. Tolerance and dependence go away when a person is no longer taking opioids.
More about opioid addiction
Summary
People who need opioids to manage cancer pain RARELY become addicted to them.
Tolerance and dependence are common when opioids are taken regularly for many weeks to months. This is not the same as addiction. These are normal physical reactions to opioids that go away if a person tapers off of opioid medications.
Try not to let fears of addiction prevent you from getting good pain management. Opioids can be a safe and effective part of pain management for the vast majority of people with cancer pain.
If you have a personal history of addiction, be open with your care team. Specialists in palliative care, pain management, or psychology can work with you to find good pain control while managing worries of addiction.